Inflammatory myofibroblastic tumor in colon.
10.4174/jkss.2012.82.1.45
- Author:
Eun Young KIM
1
;
In Kyu LEE
;
Yoon Suk LEE
;
Naery YANG
;
Dong Jin CHUNG
;
Kwang il YIM
;
Jin Il KIM
;
Seung Taek OH
Author Information
1. Department of Surgery, The Catholic University of Korea School of Medicine, Seoul, Korea. cmcgslee@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Inflammatory myofibroblastic tumor;
Colon
- MeSH:
Actins;
Adult;
Child;
Colon;
Colon, Descending;
Colonoscopy;
Defecation;
Desmin;
Hemorrhage;
Humans;
Hyalin;
Lymphocytes;
Lymphoma;
Mucous Membrane;
Muscle, Smooth;
Myofibroblasts;
Plasma Cells;
Ulcer;
Vimentin;
Young Adult
- From:Journal of the Korean Surgical Society
2012;82(1):45-49
- CountryRepublic of Korea
- Language:English
-
Abstract:
Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal solid tumor commonly documented in children and young adults. Here, we report a case of IMT in colon confirmed pathologically after laparoscopic anterior resection. A 35-year-old man presented with anal bleeding after defecation for 2 weeks. Colonoscopy demonstrated a mass with shallow ulceration in the central area and irregular margin accompanied by intact mucosa in the descending colon. Computer tomography showed a well-demarcated and homogenous solitary mass in the descending colon. We performed laparoscopic anterior resection. This case was diagnosed as IMT after microscopic examination. The tumor was composed of a proliferation of spindle-shaped cells arranged in the hyaline material with chronic inflammatory cells, composed mainly of plasma cells and lymphocytes. Immunohistochemically, tumor cells were positive for smooth muscle actin, and vimentin, and negative for desmin, CD117 (c-kit), anaplastic lymphoma kinase-1.
