Risk factors associated with cardiac valve calcification in maintenance hemodialysis patients and its effect on long-term prognosis
10.3969/j.issn.1673-4130.2024.16.021
- VernacularTitle:维持性血液透析患者心脏瓣膜钙化的相关风险因素及其对远期预后的影响
- Author:
Jing LUO
1
;
Xingwei YE
Author Information
1. 重庆医科大学附属第一医院第一分院血透室,重庆 400015
- Keywords:
hemodialysis;
cardiac valve calcification;
prognosis
- From:
International Journal of Laboratory Medicine
2024;45(16):2034-2037,2043
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors associated with cardiac valve calcification(CVC)in main-tenance hemodialysis patients and its effect on long-term prognosis.Methods A total of 157 patients with ma-intenance hemodialysis who underwent echocardiography in the hospital from January 1,2016 to January 1,2018 were retrospectively analyzed.The subjects were divided into 101 cases in non-CVC group and 56 cases in CVC group according to the results of cardiac ultrasound examination,and the clinical data were compared be-tween the two groups.Multivariate Logistic regression model was used to analyze the risk factors of CVC in maintenance hemodialysis patients.Kaplan-Meier survival curve and Cox regression model were used to ana-lyze the relationship between CVC and all-cause death in maintenance hemodialysis patients.Results The dia-betes history ratio,triglyceride,serum corrected calcium,serum phosphorus and C-reactive protein(CRP)lev-els in CVC group were higher than those in non-CVC group,and the serum albumin level was lower than that in non-CVC group,with statistical significance(P＜0.05).CRP,diabetes history,serum albumin＜35 g/L,serum corrected calcium＞2.35 mmol/L and high serum phosphorus were independent risk factors for CVC in maintenance hemodialysis patients(P＜0.05).CVC,age,serum albumin＜35 g/L and high serum phos-phorus were independent risk factors for all-cause death in maintenance hemodialysis patients(P＜0.05).Conclusion CRP,diabetes history,serum albumin＜35 g/L,serum corrected calcium and high serum phos-phorus are closely related to the occurrence of CVC in maintenance hemodialysis patients,and CVC,age,ser-um albumin＜35 g/L and high serum phosphorus are correlated with long-term all-cause death in mainte-nance hemodialysis patients.
