Advances in the function and clinical study of miRNA in nonalcoholic fatty liver disease

VernacularTitle:非酒精性脂肪性肝病中miRNA的功能及临床研究进展
Author: Yun XU ¹ ; Tianwen YANG ; Xin ZUO
Author Information

1. 重庆市第六人民医院消化内科,重庆 400060
Keywords: non-alcoholic fatty liver disease; microRNA; prognosis
From: International Journal of Laboratory Medicine 2024;45(15):1883-1886
CountryChina
Language:Chinese
Abstract: Non-alcoholic fatty liver disease(NAFLD)has become the most important cause of chronic liver disease,and its pathogenic mechanism is very complex.microRNA(miRNA)are widely distributed non-cod-ing RNA.miRNA play an important regulatory role in the pathogenesis and progression of various chronic liv-er diseases,including NAFLD,and may even be used as diagnostic indicators or even therapeutic targets for liver diseases.As a non-invasive biological indicator,a large number of research data show that miRNA has important clinical value in the diagnosis and prognosis of NAFLD.This article provides a review of the re-search progress related to the pathogenic mechanism and clinical diagnostic value of miRNA in NAFLD.