Research progress on circulating tumor RNA in tumor diagnosis and treatment
10.3969/j.issn.1673-4130.2024.13.023
- VernacularTitle:循环肿瘤RNA在肿瘤诊疗中的研究进展
- Author:
Yang SU
1
;
Qiuyue XU
;
Yong DUAN
Author Information
1. 昆明医科大学第一附属医院医学检验科/云南省检验医学重点实验室/云南省医学检验临床研究中心,云南昆明 650032
- Keywords:
liquid biopsy;
circulating tumor RNA;
tumor diagnosis and treatment;
clinical applica-tion
- From:
International Journal of Laboratory Medicine
2024;45(13):1651-1655
- CountryChina
- Language:Chinese
-
Abstract:
Tumor is a major public health problem that seriously threatens human health.Liquid biopsy plays a crucial role in early diagnosis of tumor,guidance of clinical targeted therapy,drug resistance monito-ring and prognosis assessment due to its features of high sensitivity,high specificity and high safety.Circulat-ing tumor RNA(ctRNA),as a member of liquid biopsy,not only carries the genetic information of tumors,but also reflects the transcriptional expression of tumor-related proteins and the regulatory mechanism of re-lated phenotypes.With the deeper understanding of ctRNA,the mechanism of its role in tumors is becoming clearer and clearer,showing good clinical application value,and it will become a trustworthy tool in clinical di-agnosis and treatment of tumors.
