Analysis of risk factors for bloodstream infection of refractory drug-resistant Pseudomonas aeruginosa
10.3969/j.issn.1673-4130.2024.12.014
- VernacularTitle:难治性耐药铜绿假单胞菌血流感染的危险因素分析
- Author:
Siting YI
1
;
Pingjuan LIU
;
Mengmin YE
Author Information
1. 中山大学附属第一医院东院检验科,广东广州 510700
- Keywords:
refractory drug-resistant Pseudomonas aeruginosa;
bloodstream infection;
risk factors
- From:
International Journal of Laboratory Medicine
2024;45(12):1482-1486
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the bloodstream infection of refractory drug-resistant Pseudomonas aeruginosa(DTR-PA)patients with clinical characteristics and risk factors.Methods Clinical data of patients with Pseudomonas aeruginosa bloodstream infection in the First Affiliated Hospital of Sun Yat-sen University from January 2017 to December 2022 were retrospectively analyzed.Multivariate Logistic regression analysis was used to explore the independent risk factors for DTR-PA bloodstream infection.Cox proportional hazards regression was used to explore the risk factors related to the death of Pseudomonas aeruginosa bloodstream in-fection.Results A total of 114 patients with Pseudomonas aeruginosa bloodstream infection were enrolled,with an average age of(51.05±17.55)years.The 28 d mortality was 14.0％(16/114),and 24 patients(21.1％,24/114)had DTR-PA.Age,ICU admission,diabetes,hypoproteinemia and septic shock were associ-ated with DTR-PA bloodstream infection(P＜0.05).Multivariate Logistic regression analysis showed that septic shock was an independent risk factor for DTR-PA bloodstream infection(P＜0.05).ICU admission was an independent risk factor for the death of patients with DTR-PA and Pseudomonas aeruginosa blood-stream infection(P＜0.05).Conclusion There are many risk factors for DTR-PA bloodstream infection.Septic shock and ICU admission are independent risk factors for DTR-PA bloodstream infection and death,respectively.
