Effects of non-pharmaceutical interventions on epidemiological characteristics of respiratory pathogens in adults
10.3969/j.issn.1673-4130.2024.12.004
- VernacularTitle:非药物干预措施对成人感染呼吸道病原体流行特征的影响
- Author:
Xue YANG
1
,
2
;
Chongyang WU
;
Li XIONG
;
Mengjiao LI
;
Yu YUAN
;
Yuling LIN
;
Yuling XIAO
;
Yi XIE
Author Information
1. 四川大学华西医院实验医学科,四川成都 610041
2. 成都中医药大学附属医院检验科,四川成都 610072
- Keywords:
non-pharmaceutical interventions;
respiratory pathogens;
epidemiological characteristics
- From:
International Journal of Laboratory Medicine
2024;45(12):1425-1430
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of non-pharmaceutical interventions(NPIs)on the prevalence of respiratory pathogens in adults,and to understand the scientific value and long-term effect of NPIs.Methods A retrospective study was conducted to collect the clinical data and laboratory examination data of adult patients with respiratory tract infection in West China Hospital,Sichuan University from 2017 to 2023,and the patho-gen,population,season and other aspects were analyzed in different periods.The analysis period included 2017 to 2019(before the implementation of NPIs),2020 to 2022(during the implementation of NPIs),and January to December 2023(after the implementation of NPIs).Results A total of 33 068 adult patients with respira-tory tract infection were included.The overall prevalence of 8 adult respiratory pathogens from 2017 to 2019(26.95％)was higher than that from 2020 to 2022(8.70％),and the difference was statistically significant(P＜0.05).There were significant differences in the prevalence of pathogens among different genders,ages and seasons in the first,middle and last three periods of NPIs implementation(P＜0.05).Before the imple-mentation of NPIs,the seasonal peak of respiratory prevalence appeared from January to March each year.With the implementation of NPIs,the seasonal peak of respiratory prevalence appeared from January to March 2020(10.09％),October to December 2021(9.32％),July to September 2022(15.23％),respectively.After the implementation of NPIs,the seasonal peak of respiratory prevalence appeared from October to December 2023(21.20％).Among the 8 pathogens,the change of prevalence of influenza A virus H1N1(2009)was the most obvious,and the prevalence was 17.42％,0.00％and 6.99％before,during and after the implementation of NPIs,respectively.Conclusion Due to the influence of NPIs and other factors,the epidemic characteristics of respiratory pathogens have changed from 2017 to 2023.Attention to the emerging characteristics of patho-gen prevalence is important for the prevention,diagnosis and control of respiratory infectious diseases during public health emergencies.
