Research progress in the prevention and treatment of carbapenem-resistant Klebsiella pneumoniae infection
10.3969/j.issn.1673-4130.2024.11.021
- VernacularTitle:碳青霉烯类耐药肺炎克雷伯菌感染的预防和治疗研究进展
- Author:
Xiaoxue DONG
1
,
2
;
Hongjuan ZHANG
;
Xinyue LI
;
Bin SHAN
Author Information
1. 昆明医科大学第一附属医院医学检验科,云南昆明 650032
2. 云南省医学检验临床研究中心,云南昆明 650032
- Keywords:
carbapenem resistance;
Klebsiella pneumoniae;
proactive screening;
prevention;
com-bination therapy
- From:
International Journal of Laboratory Medicine
2024;45(11):1386-1391
- CountryChina
- Language:Chinese
-
Abstract:
Carbapenem-resistant Enterobacteriaceae bacteria are widespread worldwide,with carbapenem-resistant Klebsiella pneumoniae being the most obvious,and these bacteria are usually resistant to clinically used antibiotics.In the context of the limited development and application of new drugs,and the unclear effica-cy of combination therapy,this article analyzes the relevant literature on the prevention,single and combina-tion therapy of carbapenem-resistant Klebsiella pneumoniae infection,and delays the occurrence of drug resist-ance through the linkage of prevention and anti-infective therapy in the case of carbapenemase epidemic and increasing antibiotic resistance,so as to provide a new strategy for preventing the spread of drug-resistant bac-teria and anti-infective therapy.
