Rhinosinusitis in children and its impact on bronchial asthma
10.3760/cma.j.issn.1673-4408.2024.10.009
- VernacularTitle:儿童鼻窦炎及其对支气管哮喘的影响
- Author:
Yuting GENG
1
;
Yu MIAO
;
Jinrong WANG
;
Jiangnan FENG
Author Information
1. 山东第一医科大学附属省立医院小儿呼吸科，济南 250021
- Keywords:
Rhinosinusitis;
Asthma;
Neutrophil;
Type 2 inflammation
- From:
International Journal of Pediatrics
2024;51(10):689-693
- CountryChina
- Language:Chinese
-
Abstract:
Asthma and rhinosinusitis are both common respiratory diseases in children，with a high rate of co-morbidity，and both affect each other.The theory of “same airway，same disease” has been confirmed in recent years.However，rhinosinusitis is often underdiagnosed，and correctly recognizing，diagnosing and treating rhinosinusitis in a timely manner is conducive to asthma control.Both rhinosinusitis and asthma are highly heterogeneous diseases，with diverse and complex inflammatory endotypes and biomarkers，including eosinophils and neutrophils.This article reviews the epidemiology of rhinosinusitis and asthma co-morbidities，the inflammatory endotypes and biomarkers of rhinosinusitis，the impact of rhinosinusitis on asthma and its mechanism of influence，and the impact of treating rhinosinusitis on asthma control.
