Advances in prevention and treatment of complications related to percutaneous intervention of atrial septal defect in children

VernacularTitle:儿童房间隔缺损经皮介入封堵相关并发症防治进展
Author: Tianyu ZHU ¹ ; Bo HAN
Author Information

1. 山东大学齐鲁医学院，济南　250021
Keywords: Children; Atrial septal defect; Interventional closure; Complications
From: International Journal of Pediatrics 2024;51(7):431-435
CountryChina
Language:Chinese
Abstract: Atrial septal defect（ASD）is one of the most common congenital heart diseases in children. Although most children with this condition may not exhibit clinical symptoms，persistent left-to-right shunting can increase the burden on the right heart and compromise cardiac function as they age. Therefore，early intervention is crucial for these children. Percutaneous intervention has superseded conventional surgery as the primary mode of treatment for secondary atrial septal defect in children. The procedure has a low rate of postoperative complications，but carries a substantial risk. Serious complications include unsatisfactory device position or embolization，cardiac erosion，atrioventricular block，thrombosis or thromboembolism，air embolism，and hemolysis. Common complications include headache or migraine，residual shunt，and vascular-related complications. This review focuses on the pathogenesis，clinical presentations，prevention and treatment of complications related to percutaneous intervention of atrial septal defect in children.