Multisystem inflammatory syndrome in children related to severe acute respiratory syndrome coronavirus 2 infection

VernacularTitle:新型冠状病毒感染相关儿童多系统炎症综合征
Author: Chunyan ZHAO ¹ ; Chaomin WAN ; Yu ZHU
Author Information

1. 四川大学华西第二医院小儿感染科　出生缺陷与相关妇儿疾病教育部重点实验室，成都　610041
Keywords: Children; SARS-CoV-2 infection; Multisystem inflammatory syndrome; Diagnosis; Treatment
From: International Journal of Pediatrics 2024;51(6):382-386
CountryChina
Language:Chinese
Abstract: Occasionally，previously healthy children develop severe hyperinflammatory syndrome shortly after infection with severe acute respiratory syndrome coronavirus 2（SARS-CoV-2），which is mainly manifested as digestive tract symptoms，skin mucosal damage and cardiovascular system involvement.This disease is known as multisystem inflammatory syndrome in children（MIS-C），which is confused with other diseases manifested as systemic acute inflammation.The pathogenesis of MIS-C is not clear yet，and it may be related to immune disorders secondary to the SARS-CoV-2 infection.At present，its diagnostic criteria are not established.This article reviews the characteristics of MIS-C and the research progress，in order to improve the pediatricians' skill in recognition，diagnosis and treatment of MIS-C.