Structure Confirmation of Three New Psychoactive Substances and Qualitative Identification of Unknown Substances
10.12116/j.issn.1004-5619.2023.330101
- VernacularTitle:3种新精神活性物质的结构确证及未知毒品的定性鉴定
- Author:
Zong-Yang NIE
1
;
Wei HU
;
Ling-Yu LI
;
Qing-Bo ZHANG
;
Xin HUANG
;
Bo LI
Author Information
1. 江西求实司法鉴定中心,江西 南昌 330006
- Keywords:
forensic medicine;
toxicological analysis;
new psychoactive substance(NPS);
phencyclidines;
synthetic cathinones;
infrared absorption spectrometry;
nuclear magnetic resonance(NMR)spectroscopy;
gas chromatography-mass spectrometry;
structural analysis
- From:
Journal of Forensic Medicine
2024;40(4):340-351
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the structural confirmation methods of three suspected new psychoac-tive substances(NPSs),and explore a more general qualitative testing method.Methods Infrared ab-sorption spectroscopy(IR),gas chromatography-mass spectrometry(GC-MS),1H-nuclear magnetic reso-nance spectroscopy(1H-NMR),13C-nuclear magnetic resonance spectroscopy(13C-NMR),19F-nuclear magnetic resonance spectroscopy(19F-NMR)and other techniques were used to identify the composi-tion and structure of 5 samples containing suspected NPS submitted by public security bureaus.Results NPSs were found in the above 5 samples,and 3 were confirmed as NPS included in the newly listed controlled substances on July 1,2024,namely 2-(methylamino)-2-(2-methylphenyl)cyclohexan-1-one(2-MDCK),2-(ethylamino)-2-(2-fluorophenyl)cyclohexan-l-one(2-FXE),1-(3,4-methylenedioxy-phenyl)-2-(dimethylamino)pentan-1-one(dipentylone),respectively.The first two substances were phen-cyclidine NPS,and the third substance was synthetic cathinone NPS.Conclusion This study systemati-cally summarizes the distinguishing features of the infrared absorption spectrometry,nuclear magnetic resonance spectroscopy and mass spectrometry of three NPSs,which can provide a reference for the qualitative identification of unknown substances.
