A Case of Metastatic Squamous Cell Carcinoma Arising from Actinic Cheilitis.
- Author:
Na Hyun KWON
1
;
Si Yong KIM
;
Gyong Moon KIM
Author Information
- Publication Type:Case Report
- Keywords: Actinic cheilitis; Squamous cell carcinoma
- MeSH: Actins; Carcinoma, Squamous Cell; Cheilitis; Follow-Up Studies; Hemorrhage; Keratosis, Actinic; Lip; Lymph Nodes; Neoplasm Metastasis; Recurrence; Ulcer
- From:Annals of Dermatology 2011;23(1):101-103
- CountryRepublic of Korea
- Language:English
- Abstract: Actinic keratosis (AK) is a common, sun-induced, pre-malignant lesion with a strong likelihood of progressing to a malignancy. The reported risk of AK progressing to squamous cell carcinoma (SCC) varies from less than 1% to 20%. Clinically, induration, pain, large size, marked hyperkeratosis, ulceration, bleeding, rapid growth, and recurrence or persistence may be markers of AK progression into SCC. The risk of SCC metastasizing ranges between 0.5% and 3%. However, SCC of the lip arising from actinic cheilitis is more prone to metastasis than cutaneous SCC, with rates of the former varying between 3% and 20%. Here we report a typical case of SCC from actinic cheilitis with metastasis to the lymph nodes during a 4-year follow-up period. To exclude SCC, we emphasize the need for regular follow-up and prompt evaluation, including careful pathologic examination for actinic cheilitis.
