CD8+ Lymphomatoid Papulosis.
- Author:
Ji Hyun SIM
1
;
You Chan KIM
Author Information
- Publication Type:Case Report
- Keywords: CD8+; Lymphomatoid papulosis
- MeSH: Adult; Axilla; Histiocytes; Humans; Immunophenotyping; Lymphocytes; Lymphomatoid Papulosis; Neutrophils; Thigh
- From:Annals of Dermatology 2011;23(1):104-107
- CountryRepublic of Korea
- Language:English
- Abstract: Lymphomatoid papulosis (LyP) is defined as a histologically malignant, but clinically benign condition. It can appear as erythematous pink to purple papules or nodules. Immunophenotyping studies of the lymphomatoid papulosis lesions have shown a predominance of a CD4 expression and negativity for CD8. However, a positive CD8 expression has rarely been reported for LyP. Herein we report on a case of CD8 positive lymphomatoid papulosis in a 43-year-old man. The patient presented with erythematous, asymptomatic papules on the left axilla and thigh. Histopathologically, there was a wedge-shaped infiltrate composed of a mixture of various cell types, including lymphocytes, histiocytes, neutrophils and large atypical lymphoid cells. Immunophenotyping revealed the neoplastic cells were positive for CD3, CD8 and CD30 and they were negative for CD4, CD20 and CD56.
