Au/Three-dimensional Graphene Hydrogel Modified Graphene Electrochemical Transistor for Highly Sensitive Detection of Dopamine
10.19756/j.issn.0253-3820.241124
- VernacularTitle:基于金/三维石墨烯水凝胶复合材料修饰的石墨烯电化学晶体管高灵敏检测多巴胺
- Author:
Ru-Ling WANG
1
;
Zhi-Wei CAI
;
Jun-Zi PAN
;
Ru-Nan TAN
;
Yun-Bin HE
;
Gang CHANG
Author Information
1. 湖北大学材料科学与工程学院,高分子材料湖北省重点实验室,功能材料绿色制备与应用教育部重点实验室,武汉 430062
- Keywords:
Dopamine;
Three-dimensional graphene;
Au nanoparticles;
Graphene transistor
- From:
Chinese Journal of Analytical Chemistry
2024;52(9):1307-1315,中插5-中插10
- CountryChina
- Language:Chinese
-
Abstract:
Three-dimensional graphene hydrogel(3DGH)was successfully prepared through a hydrothermal method,followed by its composition with gold nanoparticles(AuNPs)to construct a highly sensitive Au/3DGH graphene electrochemical transistor(GECT)dopamine(DA)sensor.AuNPs are efficient electrocatalytic materials.However,their tendency to aggregate during electrodeposition hinds the practical application.The porous and interconnected network structure of 3DGH provided abundant attachment sites,effectively preventing AuNPs aggregation.By modifying the sensor's gate with Au/3DGH,the excellent electrocatalytic performance of Au/3DGH towards DA and the high sensitivity of GECT were utilized to achieve highly sensitive detection of DA.The sensor exhibited a low detection limit of 20 nmol/L and a linear range of 20 nmol/L to 2.5 mmol/L.Remarkably,the sensor showed high sensitivity,excellent selectivity and strong stability,and hold great potnetial in highly sensitive portable detection of DA in disease prevention and clinical monitoring.
