Predictive value of eosinophil percentage and nasal endoscopy score for recurrence in patients with chronic sinusitis with nasal polyps complicating asthma
10.16066/j.1672-7002.2024.11.010
- VernacularTitle:嗜酸性粒细胞百分比和鼻内镜评分对慢性鼻窦炎伴鼻息肉并发哮喘患者复发的预测价值
- Author:
Huifang LIU
1
,
2
,
3
;
Yisong YAO
;
Jingyan WANG
;
Jianwei WANG
;
Yujuan YANG
;
Yu ZHANG
;
Xicheng SONG
Author Information
1. 滨州医学院第二临床医学院,山东 烟台 264003
2. 青岛大学附属烟台毓璜顶医院耳鼻咽喉头颈外科,山东 烟台 264000
3. 山东省耳鼻咽喉科疾病临床研究中心,山东 烟台 264000
- Keywords:
Sinusitis;
Nasal Polyps;
Asthma;
Eosinophils;
Endoscopy;
nasal endoscopy score;
nasal polyp recurrence
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2024;31(11):727-731
- CountryChina
- Language:Chinese
-
Abstract:
[ABSTRACT]OBJECTIVE To analyze the risk factors for relapse in patients with chronic rhinosinusitis with nasal polyps(CRSwNP)combined with asthm and provide favorable information for precise treatment and healthy prognosis of patients with CRSwNP combined with asthma.METHODS The clinical data of 161 patients with chronic rhinosinusitis with nasal polyps(CRSwNP)combined with asthm who underwent endoscopic surgery at the Department of Otolaryngology Head and Neck Surgery,Yantai Yuhuanding Hospital,affiliated to Qingdao University,from January 2016 to June 2021 were selected.Based on Lasso's Cox regression analysis and multifactorial Cox regression analysis,the associated risk factors were investigated,and the area under curve(AUC)was calculated to determine the performance of the model.Finally,the Kaplan-Meier(K-M)curves were plotted for the relevant influencing factors.RESULTS The Age[HR(95%CI):0.96(0.948-0.98),P<0.001],gender[HR(95%CI):1.94(1.21-3.14),P=0.006],tissue eosinophil percentage[HR(95%CI):1.01(1.01-1.02),P=0.004],and endoscopic nasal polyp score[HR(95%CI):0.86(0.78-0.96),P=0.005]were highly correlated with recurrence in patients with CRSwNP combined with asthma.Patients with CRSwNP combined with asthma had a higher likelihood of relapse after treatment when the tissue Eos%was>21.28%and the endoscopic nasal polyp score was>4.CONCLUSION The age,gender,tissue eosinophil percentage and endoscopic nasal polyp score are independent risk factors for disease recurrence in patients with CRSwNP combined with asthma.
