Analysis of the characteristics of temporary abnormal IPCL changes in the surgical area after CO2 laser resection for early glottic laryngeal cancer
10.16066/j.1672-7002.2024.11.001
- VernacularTitle:早期声门型喉癌CO2激光切除术后术区暂时性异常上皮内乳头样毛细血管袢的变化特点分析
- Author:
Xiaohong LIU
1
;
Meng XIE
;
Yao SHI
;
Nan CAO
;
Haonan YANG
;
Xiaoyong REN
;
Huanan LUO
Author Information
1. 西安交通大学第二附属医院耳鼻咽喉头颈外科,陕西 西安 710004
- Keywords:
Laryngeal Neoplasms;
CO2 Laser;
early glottic carcinoma;
intraepithelial papillary capillary loop;
narrowband imaging endoscopy;
mucosal stability
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2024;31(11):681-685
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the changes of temporary abnormal intraepithelial papillary capillary loop(IPCL)in the surgical area of early glottic laryngeal cancer after CO2 laser resection.METHODS A retrospective study was conducted on early-stage glottic carcinoma patients who visited the Department of Otolaryngology,Head and Neck Surgery at the Second Affiliated Hospital from January 2017 to November 2023.Patients who underwent CO2 laser surgery accepted electronic laryngoscopy examination at 1 month,3 months,and 6 months postoperatively(including white light endoscopy and narrowband imaging endoscopy(NBI),and their medical history,treatment methods,laryngoscopy images,imaging data,and pathological results before and after treatment were systematically collected.The changes in laryngoscopy characteristics at different follow-up times after surgery were analyzed.RESULTS This study included 55 patients with non recurrent early glottic carcinoma who underwent CO2 laser surgery.At 1 month,3 months,and 6 months after surgery,there were significant differences in the proportion of patients with pseudomembrane coverage(72.73%vs.25.45%vs.7.27%),granulation formation(60.00%vs.34.55%vs.1.82%),and abnormal IPCL(23.64%vs.7.27%vs.0.00%)on the surface of the surgical area(P<0.001),and abnormal IPCL(mainly type Va and Vb)can be observed under NBI endoscopy from 1 month to 3 months after surgery.Within 6 months after surgery,the pseudomembrane detachment,granulation regression,scar formation,and abnormal IPCL in the surgical area disappeared.CONCLUSION Early glottic carcinoma patients may experience temporary abnormal IPCL within 3 months after receiving CO2 laser resection,but the abnormal IPCL could disappear within 6 months after surgery for some patients.Therefore,close observation is necessary within 6 months after surgery and there is no need for urgent biopsy.
