Key points for differential diagnosis between nasal NK/T-Cell lymphoma and chronic rhinosinusitis
10.16066/j.1672-7002.2024.10.007
- VernacularTitle:鼻型NK/T细胞淋巴瘤与慢性鼻窦炎的鉴别诊断要点
- Author:
Yi DONG
1
;
Shunjiu CUI
;
Qian HUANG
;
Yan SUN
;
Yunfu LIU
Author Information
1. 首都医科大学附属北京同仁医院 耳鼻咽喉头颈外科,耳鼻咽喉头颈科学教育部重点实验室(首都医科大学),北京 100730
- Keywords:
Diagnosis,Differential;
Magnetic Resonance Imaging;
Tomography,X-Ray Computed;
Endoscopy;
NK/T-cell lymphoma
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2024;31(10):642-646
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To compare the clinical characteristics of natural killer/T-cell lymphoma(NKTL),and chronic rhinosinusitis(CRS),analyzing key points for differential diagnosis.METHODS Data from 29 nasal NKTL cases and 54 CRS cases were collected and compared,including medical history,clinical presentations,and imaging data.RESULTS The NKTL group had a shorter duration of symptom appearance(P<0.001)and more frequent symptoms of bloody nasal discharge(P=0.002).There was diffuse mucosal swelling of the turbinates and nasal septum(P<0.001),and signs of structural destruction within the nasal cavity(P=0.024).MRI more frequently showed involvement of the inferior turbinate(P=0.034),nasal septum(P<0.001),nasopharynx(P=0.002),and skull base(P=0.024),with cast-like changes or extranasal infiltration.The CRS group more frequently reported symptoms of olfactory reduction(P<0.001),swelling in the middle nasal meatus,and nasal masses(P<0.001).CT more commonly showed sinus bone hyperplasia(P=0.002).CONCLUSION Compared to CRS,nasal NKTL has a shorter symptom duration,commonly presents with diffuse nasal swelling and structural destruction both inside and outside the nasal cavity.MRI frequently shows involvement of the inferior turbinate,nasal septum,nasopharynx,and skull base,along with cast-like features and skip infiltration.
