Teratomas in Children.
- Author:
Jong In LEE
1
;
Poong Man JUNG
Author Information
- Publication Type:Original Article
- Keywords: Teratoma; Fetus-in-fetu; Endodermal sinus tumor; Embryonal carcinoma
- MeSH: alpha-Fetoproteins; Carcinoma, Embryonal; Chemotherapy, Adjuvant; Child*; Colon; Diagnosis; Drug Therapy; Endodermal Sinus Tumor; Female; Humans; Sacrococcygeal Region; Teratoma*
- From:Journal of the Korean Association of Pediatric Surgeons 1999;5(1):1-14
- CountryRepublic of Korea
- Language:Korean
- Abstract: Among 60 children with teratoma, forty-three (71.7 percent) were girls and 17 (28.3 percent) boys. Primary sites were sacrococcygeal in 30 patients (50 percent), retroperitoneal in 12 (20 percent), ovarian in 11 (18.3 percent), testicular in 3 (5 percent), and one in each of nasopharyngeal, gastric, hepatic and pancreatic (1.6 percent, respectively). Fifty-five (91.7 percent) teratomas were benign and 5 (8.3 percent) malignant. Malignant teratomas were detected only at sacrococcygeal region (16.7 percent). Older than 2 months of age at diagnosis, presence of urinary and colonic obstructive symptoms, multiple masses and elevated serum alpha-fetoprotein were indicators of malignancy in sacrococcygeal region. Tumor size, presence of calcification, and gross appearance (cystic or solid) did not correlate with malignant nature. Thirteen (21.7 percent) cases were associated with other anomalies. For the immature teratoma, the operative resection without adjuvant chemotherapy was enough. Three malignant cases were survived, one with chemotheapy for 3 years and the others without chemotherapy for 5 and 10 years.
