Evaluation of efficacy of intranasal branches neurotomy of vidian nerve in persistent moderate-severe allergic rhinitis
10.16066/j.1672-7002.2024.08.007
- VernacularTitle:翼管神经分支切断术在持续性中重度变应性鼻炎中的疗效评估
- Author:
Xuefeng LIU
1
;
Mengsheng YANG
;
Linlin CHAI
;
Xudong WEI
;
Jian HE
;
Xiaorong DONG
Author Information
1. 甘肃省人民医院耳鼻咽喉头颈外科,甘肃 兰州 730000
- Keywords:
Rhinitis,Allergic;
Nitric Oxide;
vidian nerve;
branches neurotomy of vidian nerve;
nose expiratory nitric oxide
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2024;31(8):510-514
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the efficacy of intranasal branches neurotomy of vidian nerve in the treatment of persistent moderate to severe allergic rhinitis. METHODS Cases diagnosed as persistent moderate-severe allergic rhinitis in our department were collected. those treated with branches neurotomy of vidian nerve were selected as the treatment group,and those treated with conservative medicine were selected as the control group. The visual analogue scale(VAS),rhinoconjunctivitis quality of life questionnaire(RQLQ),Nitric oxide in nose(nNO) and medication score evaluation of two groups of cases were evaluated respectively short-term(<1 year),medium-term(1 to 3 years) and long-term prognosis of outcome(3 to 5 years). RESULTS The short-term,mid-term and long-term postoperative VAS(2.26±0.75,2.30±0.63,2.49±0.57),RQLQ(0.55±0.11,0.55±0.11,1.00±0.12),nNO[(464.62±75.84)ppb,(378.63±110.21)ppb,(368.23±104.25)ppb]and medication scores (2.50±1.03,2.54±0.99,2.95±0.93) were significantly lower than those before operation[6.76±0.58,3.35±0.40,(696.64±132.69)ppb,5.17±1.50)]. The VAS,RQLQ,nNO and medication scores of the control group were lower than those of the control group at the corresponding time points(all P<0.05). One patient developed blindness in the right eye after interventional treatment due to epistaxis 21 days after operation,but no serious complications directly related to intranasal branches neurotomy of vidian nerve occurred. CONCLUSION The branches neurotomy of vidian nerve have a positive outcome in short,medium and long-term for persistent moderate to severe allergic rhinitis,the operation is safe and effective.
