Application of different nutritional support modes in early stage for severe mechanical ventilation patients
10.3760/cma.j.issn.1674-2907.2012.15.017
- VernacularTitle:早期不同营养支持方式在机械通气重症患者中的应用
- Author:
Yuan-Fen MOU
1
;
Qing-Zhou FENG
Author Information
1. 广东省深圳市第七人民医院
- Keywords:
Nutritional support;
Parenteral nutrition;
Enteral Nutrition;
Combined enteral and parenteral nutrition;
Mechanical ventilation
- From:
Chinese Journal of Modern Nursing
2012;18(15):1790-1792
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore three nutritional support mode in early stage on curative effect and outcome in the severe patients with mechanical ventilation and provide references for the clinic.Methods A total of 90 patients with mechanical ventilation from February 2009 to December 2011 were randomly divided into group A,B and C with 30 cases in every group,and were recevied parenteral nutrition(PN),enteral nutrition(EN)and combined enteral and parenteral nutrition(CEPN),respectively.The nutrition indexes,the immune indexes and the level of plasma endotoxin were mensurated in the 1st day and the 7th day after mechanical ventilation.The complications and the condition changes were carefully observed.Results Among 90 cases,57 cases were successfully detached from the respirator,at early stage,25 cases died,32 cases had complicatinns.All the observation indexes including nitrogen balance,albumin,IgA,IgG,the level of plasma endotoxi,the cases with complication,and the cases detached from respirator were recorded in the 7th day after mechanical ventilation,group A(PN):(2.3±1.2)g/d,(30.6±2.7),(1.4±0.5),(7.8±2.1) g/L,(37.1 ±6.3) pg/ml,17 cases,13 cases; group B(EN):(4.2 ±0.5) g/d,(33.5 ±1.8),(2.5 ±0.3),(13.6 ±1.5) g/L,(49.7 ±7.3) pg/ml,9 cases,21 cases,group C(CEPN):(5.8 ±0.8) g/d,(35.8 ±1.7),(2.5 ± 0.2),(13.9±1.7) g/L,(50.3 ±7.1) pg/ml,23 cases,6 cases.The differences between all the observation indexes in group B and C were superior to group A,which showed statistically significant difference(P ＜0.05).The difference of nutrition indexes and the incidence of complication was statistically significant between group C and group B (P ＜ 0.05 ).Conclusions EN combined with PN is an reasonable and effective nutrition support mode for patients with mechanical ventilation. It can improve the curative effects,and reduce the incidence of complication.
