Effect of hyperoxia solution and hypertonic saline infusion on the arteries blood gas analysis of rabbits with traumatic hemorrhagic shock
10.3760/cma.j.issn.1674-2907.2012.14.009
- VernacularTitle:静脉输注高氧液和高渗盐水对创伤性失血性休克兔动脉血气的影响
- Author:
Huai-Ning HU
1
;
Da-Jun WANG
;
Ying-Ying LIU
;
Tie XU
Author Information
1. 徐州医学院
- Keywords:
Rabbit;
Hyperoxia solution;
Hypertonic saline;
Traumatic hemorrhagic shock;
Blood gas analysis
- From:
Chinese Journal of Modern Nursing
2012;18(14):1630-1632
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of hyperoxia solution and hypertonic saline infusion on arteries blood gas analysis of traumatic hemorrhagic shock rabbits,and interaction of hyperoxia solution and hypertonic saline.Methods Forty rabbits established into traumatic hemorrhagic shock model by Lamson' s method.Post hoc analysis was adopted in trial according to hyperoxia solution and hypertonic saline and 40 rabbits were divided into four groups(n =10):saline(NS) group,normal hyperoxic solution (NSO) group,hypertonic saline(HS) group,hyperosmotic-hyperoxic solution(HSO) group.Then blood samples were collected at pre-shock,post-shock,the end of limited resuscitation and hemostatic resuscitation for blood gas analysis.Results At the pre-shock,post-shock stages,PaCO2 and PaO2 were no significant difference in each groups ( P ＞0.05 ).At the end of limited resuscitation and hemostatic resuscitation stage,PaCO2 in NSO group (33.50 ±5.93),(37.22 ±6.74) mm Hg,(31.70 ±7.39),(35.10 ±7.56 )mm Hg in HS group,HSO group(38.70 ±4.92),(41.80 ± 5.51 )mm Hg were higher than that in NS group ( 27.40 ± 3.60 ),( 30.83 ± 2.79 ) mm Hg (F =6.894,4.287,respectively ;P ＜ 0.05 ),but there were no cross correlation between hypertonic saline and hyperoxia solution ( P ＞ 0.05).There were no significant difference in PaO2 in each groups at the end of limited resuscitation and hemostatic resuscitation stage ( P ＞ 0.05 ).Conclusions Both hyperoxia solution and hypertonic saline can effectively relieve hyperventilation,but there is no interaction between them.
