Clinical Features of Pyogenic Liver Abscess according to Age Group.
- Author:
Joo Ho PARK
1
;
Tae Hee LEE
;
Sung Tae KIM
;
Jang Han JUNG
;
Yong Seok KIM
;
Sun Moon KIM
;
Euyi Hyeog IM
;
Kyu Chan HUH
;
Young Woo CHOI
;
Young Woo KANG
Author Information
- Publication Type:Original Article ; Comparative Study ; English Abstract
- Keywords: Pyogenic liver abscess; Age; Klebsiella pneumoniae
- MeSH: Adult; Age Factors; Aged; Aged, 80 and over; Bacteria/isolation & purification; Blood Cell Count; Blood Chemical Analysis; Female; Humans; Liver Abscess, Pyogenic/*diagnosis/microbiology/therapy; Male; Middle Aged; Prognosis; Retrospective Studies; Sex Factors; Urinalysis
- From:The Korean Journal of Gastroenterology 2010;56(2):90-96
- CountryRepublic of Korea
- Language:Korean
- Abstract: BACKGROUND/AIMS: Pyogenic liver abscess remains a major diagnostic and therapeutic challenge, despite advances in diagnostic technology and new strategies for treatment. This study was conducted to compare the differences in clinical features and outcomes of pyogenic liver abscess according to age. METHODS: In total, 166 patients were enrolled and included 63 (<65 years old, group I), 62 (65-74 years old, group II), 41 (>75 years old, group III) patients in each group. We reviewed the medical records retrospectively including etiology, underlying diseases, characteristics of the liver abscess, laboratory and microbiologic findings, treatment, and outcome of the patients. RESULTS: Group I had higher prevalence rates of male patients and chronic alcoholics, but lower prevalence rates of biliary disease, hypertension, and malignancy. In laboratory findings, group II had higher incidence of thrombocytopenia, elevated blood urea nitrogen and creatinine. There were no differences in symptoms and microbiologic findings in blood and pus among the three groups. Liver abscesses were more common in right liver in Group I. The lengths of stay and the treatment modalities were similar in three groups. CONCLUSIONS: Although there were differences in sex ratio, etiology, underlying disease among the different age groups, they did not cause difference in treatment and clinical outcome of pyogenic liver abscess. Thus, we recommend active treatments in patients of all age.
