Diagnostic value of probe-based confocal laser microendoscopy in differential diagnosis of fundic gland polyps
10.16016/j.2097-0927.202310082
- VernacularTitle:探头式共聚焦激光显微内镜对胃底腺息肉的诊断价值
- Author:
Ziyi WANG
1
;
Jing CHEN
;
Xueqian ZHOU
;
Jia YANG
;
Xiangyong MENG
;
Jing WU
;
Wensheng CHEN
Author Information
1. 400038 重庆,陆军军医大学(第三军医大学)第一附属医院消化内科
- Keywords:
gastric polyp;
fundic gland polyps;
probe-based confocal laser endomicroscopy
- From:
Journal of Army Medical University
2024;46(10):1150-1157
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of probe-based confocal laser endomicroscopy(pCLE)in the differential diagnosis of fundic gland polyps.Methods A total of 63 patients who underwent conventional white light image(WLI)and suggested with gastric polyps in our gastroenterology endoscopy center during June and December 2023 were enrolled,and their clinical data,WLI,narrow band images(NBI),pCLE images and postoperative histopathological findings were collected.The characteristics of fundic gland polyps under pCLE were statistically verified,and the sensitivity,specificity,accuracy and consistency of different endoscopic diagnoses were calculated respectively.Results Under pCLE,fundic gland polyps were mainly manifested as elongated gastric pit opening,"hand-in-hand"gastric pit opening,well-arranged blood vessels around the pit opening,and no luciferin oozing.The sensitivity,specificity,accuracy of WLI were 72.73％,75.00％,73.13％and 0.343 for fundic gland polyps,and 81.82％,71.43％,71.64％and 0.354 for hyperplastic polyps,respectively.While,the above values of NBI were 87.27％,83.33％,86.57％and 0.673 for fundic gland polyps,and 81.82％,85.71％,85.07％and 0.554 for hyperplastic polyps;and those of pCLE were 92.73％,91.67％,92.53％and 0.769 for fundic gland polyps,and 90.91％,94.64％,94.03％and 0.797 for hyperplastic polyps pCLE had better sensitivity,specificity and accuracy than WLI and NBI,and had the results consistent with histopathological findings.Conclusion pCLE can be used in the differential diagnosis of fundic gland polyps.
