Pancreatic cystic neoplasms:research progress in diagnosis and treatment of endoscopic ultrasound

VernacularTitle:胰腺囊性肿瘤:超声内镜的诊治研究进展
Author: Xinyue WANG ¹ ; Liqi SUN ; Haojie HUANG ; Zhendong JIN
Author Information

1. 海军军医大学(第二军医大学)第一附属医院消化内科,上海 200433
Keywords: pancreatic cystic neoplasms; mucinous neoplasms; non-mucinous neoplasms; endoscopic ultrasound; ablation
From: Academic Journal of Naval Medical University 2024;45(10):1281-1287
CountryChina
Language:Chinese
Abstract: Pancreatic cystic neoplasm(PCN)is a category of pancreatic tumors with significant heterogeneity.In recent years,the detection rate of PCN has been increasing,and it has gradually become a concern of clinicians.Endoscopic ultrasound(EUS)can be close to the pancreas for scanning and biopsy,and it has certain advantages in the diagnosis and treatment of PCN.This review mainly summarizes the latest progress of EUS in the diagnosis and treatment of PCN.Cyst fluid molecular markers,such as Kirsten rat sarcoma viral oncogene homolog,GNAS complex locus,Von Hippel-Lindau tumor suppressor gene,as well as emerging endoscopic technologies such as EUS-guided needle based confocal laser endomicroscopy and through-the-needle biopsy,have all showed the potential to significantly improve the diagnostic accuracy of PCN.EUS-guided ablation is an emerging minimally invasive treatment technique for PCN,with the efficacy and safety of chemical ablation being supported by a substantial amount of research.