Impact of the multichemotherapy in the change of situation of the leprosy epidemiology
- Author:
Minh Tan Truong
- Publication Type:Journal Article
- Keywords:
leprosy
- MeSH:
Leprosy;
Leprostatic Agents;
epidemiology
- From:Journal of Practical Medicine
2002;435(11):48-51
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
In order to evaluate how multitherapy affects on epidemiological picture of leprosy in Kh¸nh Hßa province, the authors have researched disease documents of 1.813 leprotic patients at Kh¸nh Hßa Provincial Dermatological Hospital from 1985 - 1999. They also carried out a sociological investigation from 2.847 normal people and 724 patients. Smear skins of 117 leprosy patients were collected randomly to find out ADN of Mycobacterium leprae by Polymerasa Chain Reaction (PCR) technique. Results showed: Using multitherapy with the combination of three drugs (Rifampicine, Clofazimine and Dapsone) have cut down leprosy incidence, detected new patients rate, under 15 year-old patients rate among new one yearly. It has increased the average age of detected new patients. It has also increased the rate of new patient register themselves in the past fifteen years. However, 5% PCRs of MB patients who stopped using multitherapy 5 years ago are still positive. This fact makes us to pay more attention on relapse of the disease, especially to whom with BI above 4+
