Studv on threshold of low temperature burns in rats
10.3760/cma.j.issn.1674-2907.2011.34.008
- VernacularTitle:大鼠低温烫伤阈值的研究
- Author:
Chun-Nuan HUO
1
;
Jian-Rong WANG
Author Information
1. 解放军总医院
- Keywords:
Low temperature;
Rat;
Nursing;
Burns;
Threshold
- From:
Chinese Journal of Modern Nursing
2011;17(34):4113-4115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore experimental evidence for prevention and treatment of low temperature burns in clinical practice.Methods A rat model of low temperature burns was established by exposing abdominal skin to temperature of 42 ～ 70 ℃.Time needed to cause burns,severity of damage,pathological changes,relation between tissue damage and temperature and mortality of animal models were studied.Results We found that skin tissue was not different between the 42 ℃ rats and normal temperature rats.45.2％ rats died in 2-3 h after exposed to 45 ℃.All rats died in 45-60 min after exposed to 50 ℃.Death time was(42.43 ±2.15)min in rats directly exposed to 55 ℃,and(66.14 ±8.61)min in rats with protection,and the difference was significant(t =7.0697,P ＜ 0.01).Microscopy revealed that wide necrosis in rats skin,subcutaneous tissue and deep muscular layer.Conclusions Low temperature burns are caused by direct exposure to temperature of 45 ～ 70 ℃ while high temperature bums are caused by direct exposure to temperature of 70 ℃ and above.Severity of damage and mortality is related to temperature,exposure time and position.
