Predictive value of inflammation scoring system based on blood routine for complicated acute pancreatitis
10.3969/j.issn.1671-8348.2024.22.014
- VernacularTitle:基于血常规的炎症评分系统对复杂性胰腺炎的预测价值
- Author:
Xiaoli HUANG
1
;
Yongliang TANG
;
Jia XU
;
Juntao YANG
;
Menggang LIU
Author Information
1. 重庆两江新区人民医院肝胆胰外科,重庆 401121
- Keywords:
acute pancreatitis;
complicated pancreatitis;
blood routine;
inflammatory index;
systemic immune inflammatory index
- From:
Chongqing Medicine
2024;53(22):3441-3446
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of the inflammation scoring system based on the blood routine for complicated acute pancreatitis(CAP).Methods The clinical data of 630 patients with a-cute pancreatitis(AP)receiving the treatment in the People's Hospital of Chongqing Liang Jiang New Area from January 2021 to January 2024 were retrospectively analyzed.The patients were divided into the mild a-cute pancreatitis(MAP)group and CAP group according to the disease severity degree.The propensity score matching was used to balance the baseline characteristics of the cases in the two groups,the differences be-tween the inflammatory scoring system based on the blood routine[neutrophile granulocyte/lymphocyte ratio(NLR),derived neutrophile granulocyte/lymphocyte ratio(dNLR),platelet/lymphocyte ratio(PLR),system-ic immune inflammatory index(SII)and systemic inflammatory response index(SIRI)]and the clinical out-come indexes within 24 h of admission were analyzed,and the logistic regression was used to analyze the risk factors of CAP.Results A total of 404 patients were included in the study by the propensity score matching,each 202 cases in the two groups.In the CAP group,there were 35 cases(16.7％)receiving intensive care unit(ICU)treatment and 4 cases(1.9％)of death.Compared with the MAP group,WBC,neutrophile granulo-cyte,CRP,BUN,amylase and lipase levels and NLR,dNLR,SII and SIRI scores in the CAP group were high-er,serum calcium and albumin levels were lower,and the differences were statistically significant(P＜0.05).The stepwise logistics regression analysis showed that CRP,albumin,lipase,serum calcium and SIRI were the independent influencing factors of CAP occurrence(P＜0.05).Conclusion The inflammation scoring system based on the blood routine could predict the CAP occurrence.
