Research progress on esketamine for preventing agitation during recovery period of pediatric general anesthesia

VernacularTitle:艾司氯胺酮预防小儿全身麻醉苏醒期躁动的研究进展
Author: Qingyu ZHAO ¹ ; Rugang AN ; Zhengquan TAN ; Guihua HUANG
Author Information

1. 遵义医科大学第三附属医院麻醉科,贵州遵义 563000
Keywords: esketamine; general anesthesia; child; agitation; review
From: Chongqing Medicine 2024;53(21):3335-3339
CountryChina
Language:Chinese
Abstract: Agitation during the recovery period after general anesthesia is a common complication after pediatric surgery,which can lead to accidents and other serious complications.Esketamine is a high-affinity noncompetitive inhibitor of N-methyl-D-aspartate(NMDA)receptors,which has both anesthetic and analgesic effects,and can be used as an adjunct drug to sedation for endotracheal intubation under general anesthesia and perioperative anesthesia.This article reviews the current research progress of esketamine in the treatment of agitation during recovery period in order to provide reference for clinical reduction of the occurrence of agita-tion in children during recovery period.