Analysis on clinicopathological features in 30 cases of ovarian clear cell carcinoma
10.3969/j.issn.1671-8348.2024.21.018
- VernacularTitle:卵巢透明细胞癌30例临床病理特征分析
- Author:
Qiuyue LIU
1
;
Rongjun ZHANG
;
Xuchong TANG
Author Information
1. 晋江市医院/上海市第六人民医院福建医院病理科,福建晋江 362200
- Keywords:
ovarian clear cell carcinoma;
endometrioid cysts;
clinicopathologic features;
differential di-agnosis
- From:
Chongqing Medicine
2024;53(21):3295-3299
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinicopathological features of ovarian clear cell carcinoma to pro-vide a basis for the differential diagnosis of whether it originates from endometrioid cyst.Methods A total of 30 patients with ovarian clear cell carcinoma receiving treatment in Jinjiang Municipal Hospital from January 2009 to December 2022 were collected as the research subjects.The patients not originating from endometrioid cysts were included in the control group(n=15)and the patients originating from endometrioid cysts were in-cluded in the observation group(n=15).Macroexamination,microscopic examination,hematoxylin-eosin stai-ning and immunohistochemical staining were used to analyze the clinicopathological characteristics.The gener-al data and pathological examination results of the two groups were statistically analyzed.Results Among the two groups,there were 22 cases(73.33％)of clear cells,3 cases(10.00％)of shoe-tack like cells,2 cases(6.67％)with about half of each cell type,and 3 cases(10.00％)of hyaline bodies or eosinophils.There were 27 cases(90.00％)of aspartic acid peptidase A(Napsin-A)positive and 29 cases(96.67％)of hepatocyte nu-clear factor-1β(HNF-1β)positive.Staging,ascites,lymph node metastasis,abdominal/pelvic metastasis,CA125,complicating endometrioid cyst,coffee-colored fluid in the sac,uneven thickness of the cyst wall,men-strual disorders and infertility all were the influencing factors of ovarian clear cell carcinoma originating from endometrioid cyst(P＜0.05).Conclusion The relevant pathological features could provide an important ref-erence base for the clinical differential diagnosis of whether ovarian clear cell carcinoma originates from endo-metrioid cysts,and it is of great significance to improve the detection rate of ovarian clear cell carcinoma.
