A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male.

Author: Sung eun CHOI ¹ ; Yoon Jin CHA ; Jisup KIM ; Hyunseo CHA ; Jayeong SEO ; Sung Uk KUH ; Sung Jun KIM ; Se Hoon KIM
Author Information

1. Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Publication Type:Case Report
Keywords: Melanotic schwannoma; Spine; Recurrence; Metastasis
MeSH: Cytoplasm; Humans; Male*; Melanosomes; Middle Aged*; Neoplasm Metastasis; Nerve Sheath Neoplasms; Neurilemmoma*; Prognosis; Recurrence; Schwann Cells; Spinal Nerves*; Spine
From:Journal of Pathology and Translational Medicine 2017;51(5):505-508
CountryRepublic of Korea
Language:English
Abstract: Melanotic schwannoma (MS) is a rare variant of nerve sheath neoplasm that shows ultrastructural and immunophenotypical features of Schwann cells but also has cytoplasmic melanosomes and is reactive for melanocytic markers as well. Unlike conventional schwannoma, which is totally benign, MS has an unpredictable prognosis and is thought to have low-malignant potential. Herein, we present a rare case of recurrent MS in lumbar spine of a 59-year-old male.