Analysis on influencing factors in fatigue status changes in patients with tumor radiotherapy
10.3969/j.issn.1671-8348.2024.18.002
- VernacularTitle:肿瘤放疗患者疲劳状况变化影响因素分析
- Author:
Feiran WANG
1
;
Hongyu CHEN
;
Dequan PANG
Author Information
1. 华北理工大学附属医院放疗科,河北唐山 063000
- Keywords:
tumor radiation therapy;
fatigue score;
heart rate variability;
autonomic neuropathy;
influencing factors
- From:
Chongqing Medicine
2024;53(18):2730-2734
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of fatigue status before and after radiotherapy in tumor patients and its influencing factors.Methods A total of 150 tumor patients with radiotherapy in the radiother-apy department of this hospital from February to September 2023 were selected as the study subjects.The general data questionnaire and the Multidimensional Fatigue Scale (MFI-20) were adopted to conduct the sur-vey.The fatigue scores and the changes in autonomic nervous function were compared between before and af-ter radiotherapy.The multifactor logistic regression was applied to analyze the influencing factors of changes in fatigue status.Results Compared with before radiotherapy,the average fatigue scores after radiotherapy were higher[(63.99±14.54)points vs. (52.75±17.18)points],low frequency (LF),and high frequency (HF),total power (TP),time domain indicators sinus heart beat RR interval standard deviation (SDNN) and the root-mean-square value of the difference between adjacent NN interval (rMSSD) were lower,LF/HF was higher,and the differences were statistically significant (P<0.05).The univariate analysis results showed that the fatigue situation had statistical difference among the patients with different clinical stages,chronic dis-ease history,pain scores,hemoglobin,lymphocyte,WBC and heart rate variability (HRV,P<0.05).The mul-tivariate logistic regression analysis results showed that the decrease of hemoglobin,WBC and HRV were the independent risk factors of fatigue aggravation (P<0.05).Conclusion It is necessary to guide the clinic to conduct the intervention on the influencing factors aggravating fatigue to improve the outcome of the patients with tumor.
