Analysis on 428 cases adverse drug reaction/event reports of antibacterial agents

VernacularTitle:428例抗生素不良反应/事件报告相关因素分析
Author: He-Zhen ZHANG ¹ ; Xue-Qin ZHOU ; Ai-Li WANG ; Li LIANG ; Jie LUO
Author Information

1. 北京大学深圳医院
Keywords: Antibacterial agents; Adverse drug reactions/events(ADR/ADE); Analysis
From: Chinese Journal of Modern Nursing 2011;17(24):2892-2894
CountryChina
Language:Chinese
Abstract: Objective To learn the adverse drug reactions/events (ADR/ADE) occurred in the characteristics and rules for clinical safe, effective and rational use of available information by analysis of 428antibacterial agents ADR/ADE Reports. Methods 428 antibacterial agents ADR/ADE Reports were statistical analyzed from Jan 1. 2007 to Dec 31. 2010 in our hospital. Results 428 cases of antibacterial agents ADR/ADE, females was slightly more than males; patients between 50 to 83 years old age were accounted for the majority (264 cases,61.68％ ) ;the cases that caused by cephalosporins were accounted for the most(239 case,55.85％ ),385 case that administered intravenously were accounted for the majority (89. 96％ ); antibacterial agents ADR/ADE main clinical manifestations of anaphylactic shock, respiratory, systemic and central nervous system damage. Condusions Strengthening antibacterial agents ADR/ADE monitoring, to decrease the occurrence of Serious ADR/ADE and ensure clinical safety, effective, rational use of drug.