Psychosocial factors influencing recurrence in patients with myasthenia gravis
10.3969/j.issn.1671-8348.2024.16.004
- VernacularTitle:影响重症肌无力患者病情复发的心理社会学因素研究
- Author:
Dalin REN
1
;
Zhe RUAN
;
Dongdong MENG
;
Ting CHANG
;
Qian YANG
Author Information
1. 空军军医大学唐都医院实验外科 西安 710038
- Keywords:
myasthenia gravis;
relapse;
risk factors;
psychology
- From:
Chongqing Medicine
2024;53(16):2421-2425
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the psychosocial factors affecting the recurrence of the patients with myasthenia gravis (MG).Methods The retrospective analysis was adopted.One hundred and sixty-one pa-tients with MG treated in the neurosurgery department of this hospital from January 2019 to January 2021 were selected as the research subjects.The psychosocial data of the patients were collected.The correlation be-tween the gender,age of onset,history of underlying diseases,body mass index (BMI),education level,occu-pational nature,per capita monthly family income,living environment,payment method of medical expenses and mental state with the disease recurrence was analyzed.Results Among 161 patients,111 cases developed the recurrence (included in the recurrence group) and 50 cases (included into the stable group).There were statistically significant differences in the age,gender and mental status between the two groups (P<0.05),but there were no statistically significant differences in the history of underlying diseases,BMI,education lev-el,occupational nature,per capita monthly household income,living environment and payment method of med-ical expenses between the two groups (P>0.05).The multivariate logistic regression analysis results showed that the age of onset (OR=0.304,95％CI:0.146-0.634) and anxiety combined with depression (OR=2.706,95％CI:1.090-6.719) were the influencing factors of the recurrence in the patients with MG (P<0.05).Conclusion It is necessary to pay special attention to MG patients with young onset age,anxiety and depression status,which are prone to relapse.
