Effect of Huaier Granules in primary liver cancer treatment:a reevaluation on systematic review
10.3969/j.issn.1671-8348.2024.12.020
- VernacularTitle:槐耳颗粒在原发性肝癌治疗中作用的系统评价再评价
- Author:
Kai LI
1
;
Chuanxin WU
;
Na WANG
;
Hang SUN
Author Information
1. 重庆医科大学附属第二医院肝胆外科,重庆 400010
- Keywords:
Huaier Granules;
primary liver cancer;
PRISMA statement;
AMSTAR2;
GRADE;
reevalu-ation on systematic review
- From:
Chongqing Medicine
2024;53(12):1864-1869,1877
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct the reevaluation on the systematic evaluation of the role of Huaier Granules in the treatment of primary liver cancer to provide the practical and reliable reference basis for clini-cal decision.Methods The literatures on the systematic evaluation of Huaier granules in the treatment of pri-mary liver cancer was retrieved.The evaluation was performed by the preferred reporting items for systematic reviews and meta-analyses(PRISMA)statement,a measure tool to assess systematic reviews(AMSTAR)2 scale and the grading of recommendations assessment,development and evaluation(GRADE)system tool.Re-sults Finally,4 literatures with a total sample size of 8 040 cases were included.In 27 items with the reported quality,the proportions of complete agreement were 66.67％,62.96％,66.67％and 70.37％,respectively.AMSTAR2 scale showed that the quality of the four articles was very low.The GRADE system tool evalua-tion showed that there were 9 medium quality evidences,8 low quality evidences and 18 extremely low quality evidences.Conclusion At present,the systematic evaluation of Huaier Granules in the treatment of primary liver cancer has different degrees of defects in the integrity of the report,methodological quality,and evidence strength of outcome indicators,which still needs more high-quality studies to provide more reliable evidence-based medical evidence to guide clinical practice.
