Study on correlation between time within glucose target range and left ventricular mass index in patients with type 2 diabetes mellitus complicating hypertension
10.3969/j.issn.1671-8348.2024.12.013
- VernacularTitle:2型糖尿病合并高血压患者葡萄糖在目标范围内时间与左心室质量指数的相关性研究
- Author:
Bo YAN
1
;
Yuan YAO
;
Xing ZHONG
;
Tianrong PAN
Author Information
1. 明光市人民医院内分泌科,安徽滁州 239000
- Keywords:
type 2 diabetes mellitus;
dynamic glucose monitoring;
time within glucose target range;
left ventricular mass index
- From:
Chongqing Medicine
2024;53(12):1823-1827
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the glucose time in range(TIR)and left ventricular mass index(LVMI)in the patients with type 2 diabetes mellitus(T2DM)complicating hyperten-sion.Methods A total of 102 inpatients with T2DM in the Mingguang Municipal People's Hospital from January to December 2022 were selected as the study subjects and conducted the continuous dynamic glucose monitoring.They were divided into the group A(TIR≤40％,n=31),group B(TIR＞40％-70％,n=41)and group C(TIR＞70％,n=30)according to the TIR level.The clinical data,laboratory indicators and echo-cardiographic parameters were collected and compared among the three groups.Results Compared with the group A,the age,disease course,systolic blood pressure and the levels of HbA1c,FPG,SCr and TG in the group C were significantly decreased,the HDL-C level was increased,and the differences were statistically sig-nificant(P＜0.05).Compared with the group B,the age and the levels of SCr,TG,HDL-C,HbA1c and FPG in the group C were decreased,and the differences were statistically significant(P＜0.05).Compared with the group A and group B,LAD,LVPW,IVS and LVMI in the group C were reduced with statistical differences(P＜0.05).The multiple linear stepwise regression analysis results showed that TIR was a protective factor for LVMI(OR=0.562,95％CI 0.413-0.673,P＜0.05),and the disease course and systolic blood pressure were the risk factors(OR=1.511,95％CI:1.067-2.947;OR=2.325,95％CI:1.086-5.574,P＜0.05).Conclusion TIR in the patients with T2DM complicating hypertension is correlated with LVMI,and the TIR level may be an influencing factor for early cardiovascular events.
