Role of neuroinflammation and white matter injury in cognitive dysfunction after subarachnoid hemorrhage
10.3969/j.issn.1671-8348.2024.11.025
- VernacularTitle:蛛网膜下腔出血后神经炎症与白质损伤在认知功能障碍中的作用
- Author:
Yunchuan CAO
1
;
Bo ZENG
;
Xiaoguo LI
;
Yajun ZHU
;
Xiaofeng ZHANG
;
Yingwen WANG
;
Xiaochuan SUN
;
Zongduo GUO
Author Information
1. 重庆医科大学附属第一医院神经外科,重庆 400016
- Keywords:
subarachnoid hemorrhage;
neuroinflammation;
white matter injury;
cognitive function;
review
- From:
Chongqing Medicine
2024;53(11):1732-1736
- CountryChina
- Language:Chinese
-
Abstract:
Subarachnoid hemorrhage (SAH) is the third common type of stroke in the world,and its mortality and disability rates have declined over the past few decades due to the advances in neuroimaging technology and endovascular interventional therapy and promotion of healthy physical examination,but long-term neurological deficits and cognitive impairment of the patients have not significantly improved,which may be related to the white matter injury (WMI) after SAH.Little attention has been paid to WMI after SAH in the past,which may be an important reason for the poor prognosis of the patients with SAH.The neuroin-flammation response is an important pathophysiological process after SAH,and the neuroinflammation after SAH can aggravate WMI.This article reviews the relationship between neuroinflammation and WMI after SAH in order to deepen the understanding of its effects on cognitive function after SAH.
