Effect of antibiotics on anal fistula formation after perianal abscess incision and drainage:a meta-analysis
10.3969/j.issn.1671-8348.2024.10.020
- VernacularTitle:抗生素对肛周脓肿切开引流术后肛瘘形成影响的meta分析
- Author:
Bo PENG
1
;
Jiawen ZHENG
Author Information
1. 江苏大学附属医院,江苏镇江 212000
- Keywords:
perianal abscess;
incision and drainage;
antibiotics;
anal fistula;
meta-analysis
- From:
Chongqing Medicine
2024;53(10):1553-1556,1562
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of antibiotics on the formation of anal fistula after peri-anal abscess surgery.Methods Database of Web of Science,PubMed,Embase,Cochrane Library,Wanfang,CNKI,VIP and China Clinical Trial Registry were searched to collect clinical studies on antibiotic therapy af-ter perianal abscess incision and drainage,and meta-analysis was performed after screening and evaluation.Results A total of eight studies were included for systematic review,including three studies were randomized controlled trials,four studies were cohort studies,and one study was case-control study.They were divided in-to randomized the controlled trial(RCT)subgroup and the observational study subgroup according to differ-ent research types,and combined analysis was conducted by using random effects model.The risk ratio(RR)of RCT subgroup was 0.71,95％CI was 0.30-1.69;The RR of observational research subgroup was 0.61,95％CI was 0.48-0.78.The total RR was 0.64,95％CI was 0.47-0.88.Conclusion The application of an-tibiotics after perianal abscess incision and drainage has a certain preventive effect on the formation of anal fis-tula.
