Risk factors and prediction model of catheter-associated urinary tract multidrug resistant bacterial infection in elderly patients
10.3969/j.issn.1671-8348.2024.10.014
- VernacularTitle:老年患者导管相关性尿路多重耐药菌感染危险因素及其预测模型
- Author:
Juan LIU
1
;
Xiaoxia ZHANG
;
Feng ZANG
;
Songqin LI
;
Zhanjie LI
;
Ting CUI
;
Ke WANG
;
Xiaoying LAI
;
Dongfang ZHANG
Author Information
1. 江苏省人民医院/南京医科大学第一附属医院感染管理处,南京 210029
- Keywords:
elderly;
multi-drug resistant bacteria;
catheter-associated urinary tract infection;
risk factors
- From:
Chongqing Medicine
2024;53(10):1519-1524
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the infection of multidrug-resistant organism(MDRO)in elderly pa-tients with catheter-associated urinary tract infection(CAUTI)and analyze the infection factors.Methods The medi-cal records of 175 elderly patients with CAUTI admitted to Jiangsu Province Hospital from January 2021 to July 2022 were selected,the distribution of MDRO infection in elderly patients with CAUTI was analyzed,and the influencing factors of MDRO infection were analyzed.The predictive value of independent risk factors for rele-vant nosocomial infections was analyzed by receiver operating characteristics(ROC)curves.Results Among the 175 elderly patients with CAUTI,87 cases(49.71％)developed MDRO infection and were included in the MDRO infection group),and 88 cases(50.29％)had no MDRO infection and were included in the non-MDRO infection group.A total of 432 MDRO pathogens were detected in the MDRO infection group,inclu-ding 415 strains of Gram-negative bacteria,accounting for 96.06％,186 strains of carbapenem-resistant Acine-tobacter baumannii(43.06％),147 strains of carbapenem-resistant Klebsiella pneumoniae(34.03％),79 strains of carbapenem-resistant Pseudomonas aeruginosa(18.29％)and 3 strains of carbapenem-resistant Escherichia coli(0.69％).There were 17 strains of Gram-positive bacteria(3.94％),all of which were methi-cillin-resistant Staphylococcus aureus.Multivariate analysis showed that the use of carbapenems,tigecycline,polymyxin,and days of central venous intubation were considered as independent risk factors.The area under the curve of MDRO infection was 0.883.Conclusion For elderly patients with CAUTI,it is necessary to take strict antimicrobial management measures,master the indications of antimicrobial application,shorten the hos-pitalization time of patients and reduce the incidence of MDRO infection.
