Meta analysis of treatment effect of total knee replacement on hemophiliac arthritis
10.3969/j.issn.1671-8348.2024.09.019
- VernacularTitle:全膝关节置换术对血友病性关节炎治疗效果的meta分析
- Author:
Xiaolu ZHANG
1
;
Xiaoyan LIU
;
Ling ZHANG
;
Maojie WU
;
Ying HE
Author Information
1. 四川大学华西医院骨科/四川大学华西护理学院,成都 610041
- Keywords:
hemophilia arthritis;
total knee arthroplasty;
rehabilitation current situation;
meta analysis
- From:
Chongqing Medicine
2024;53(9):1384-1390
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effect of total knee replacement (TKA) in patients with hemophilia arthritis (HA) using meta analysis,and to summarize the quality of postoperative joint func-tion rehabilitation and complication rates in patients with hemophilia to provide the evidence-based medical ba-sis for clinical intervention.Methods The studied on the functional rehabilitation after TKA were retrieved from the databases of CNKI,CBM,WanFang,VIP,Pubmed,Web of science and Embase.The retrieval time limit was from the establishment of each database to February 2023.The two evaluators independently screened the literatures,extracted the data and evaluated the quality of included studies.Then the Stata 15 software was used for conducting the meta analysis.Results A total of 20 studies were included,including 686 patients and 897 joints.The mean follow-up time was 6 months to 18 years.The clinical dimension score of the knee association score (KSS) was 81.20 (95％CI:75.36-87.03).The KSS functional dimension score was 81.95 (95％CI:71.34-92.57),the complications occurrence rate was 0.16 (95％CI:0.11-0.22),and the American Hospital for Special Surgery Knee Sale (HHS) score was 88.72 (95％CI:85.11-92.33),the knee joint range of motion (ROM) was 85.06 (95％CI:75.73-94.39),and the flexion contracture score was 5.760 (95％CI:2.62-8.91).Conclusion The present evidence shows that TKA is effective in improving the joint function in the patients with HA,ensure the quality of postoperative rehabilitation,which could serve as a treatment option for the patients with HA.
