New Parameters for Left Ventricular Function in Atrial Fibrillation: Based on the Relationship between RR Interval and Performance.
10.3346/jkms.2005.20.1.20
- Author:
Hong Sook KO
1
;
Chee Jeong KIM
;
Wang Seong RYU
Author Information
1. Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea. cjkim@cau.ac.kr
- Publication Type:Original Article
- Keywords:
Atrial Fibrillation;
Electrocardiography;
Echocardiography, Doppler, Pulsed;
Stroke Volume
- MeSH:
Age Factors;
Aged;
Atrial Fibrillation/*metabolism;
Atrial Function, Left;
Echocardiography;
Echocardiography, Doppler, Pulsed;
Electrocardiography;
Female;
Heart/physiology;
Heart Ventricles;
Hemodynamic Processes;
Humans;
Male;
Middle Aged;
Models, Theoretical;
Multivariate Analysis;
Myocardial Contraction;
Myocardium/pathology;
Time Factors;
*Ventricular Function, Left
- From:Journal of Korean Medical Science
2005;20(1):20-25
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was designed to obtain new parameters representing left ventricular (LV) function independent of irregular RR intervals in atrial fibrillation (AF). AF patients were divided into Normal (n=9) and LV Dysfunction (n=9) groups. The relations between LV outflow peak ejection velocity (Vpe) and preceding (RR-1) or prepreceding RR intervals (RR-2) were obtained using logarithmic equations, from which the squared correlation coefficient (r2), slope, Vpe at RR-1 or RR-2=1 sec (Vpe-1), and the ratio of slope to Vpe-1 (Slope/Vpe-1) were calculated. Among the parameters between RR-1 and Vpe, Slope/Vpe-1 was higher in LV Dysfunction group than in Normal group (p=0.05). When only coordinates with RR-1 from 0.6 to 1 sec were included, Slope/Vpe-1 (p=0.001) was higher in LV Dysfunction group than in Normal group. Among the parameters between RR-2 and Vpe, Slope/Vpe-1, slope, and r2 were different between the two groups. In multivariate analysis, Slope/Vpe-1 between RR-2 and Vpe was only independent parameter. However, Slope/Vpe-1 between RR-1 and Vpe in the coordinates with RR-1 from 0.6 to 1 sec had the highest discriminating power. New parameters derived from the relations between RR intervals and LV performance might be useful to evaluate LV function quantitatively in AF.