Research progress of ferroptosis in Parkinson's disease
10.3969/j.issn.1671-8348.2024.08.027
- VernacularTitle:铁死亡在帕金森病中的研究进展
- Author:
Qingxin SONG
1
,
2
;
Denghui LI
Author Information
1. 临沂市人民医院神经外科,山东临沂 276003
2. 四川大学华西医院神经外科,成都 610041
- Keywords:
ferroptosis;
lipid peroxidation;
parkinson's disease;
iron metabolism;
review
- From:
Chongqing Medicine
2024;53(8):1266-1269
- CountryChina
- Language:Chinese
-
Abstract:
Ferroptosis is a newly discovered form of programmed cell death,which is mainly character-ized by the accumulation of iron-dependent lipid peroxidation in cells.Studies have found that ferroptosis may play a key role in the occurrence and development of Parkinson's disease.This article reviews the molecular regulation mechanism of ferroptosis and its research progress in Parkinson's disease,in order to provide the theoretical basis and new ideas for targeted ferroptosis in the treatment of Parkinson's disease.
