Research progress in protective effects of remote ischemic conditioning on different organs

VernacularTitle:远端缺血处理对不同器官保护作用的研究进展
Author: Wenlang LI ¹ ; Guangyou DUAN ; He HUANG
Author Information

1. 重庆医科大学附属第二医院麻醉科,重庆 400010
Keywords: remote ischemic preconditioning; remote ischemic conditioning; organ protection; ischemia/reperfusion injury; review
From: Chongqing Medicine 2024;53(8):1254-1259,1265
CountryChina
Language:Chinese
Abstract: Remote ischemic conditioning (RIC) is a means of playing the systemic organ protective effect by transient ischemia/reperfusion of the limb,thus reduces the damage caused by more severe ischemic events.RIC can be applied before,during and after ischemic events;among them,the application before ische-mia is relatively more,which is called the remote ischemic preconditioning (RIPC).Researches have shown that RIC has considerable clinical translation value characterizing by non-invasion,economy,safety and effect. Although the specific mechanism needs to continue to be explored,but its protective targets are quite exten-sive.Especially for the heart,RIC seems to have favorable protective effects on the heart under almost all pathological conditions.Moreover,RIC has a certain degree of protective effect on the nervous system,lungs,livers and kidneys.Based on this,this article reviews the protective effects of RIC in different organs and its possible mechanisms.