Analysis on clinical characteristics and drug resistance of postoperative incision infection caused by Mycoplasma hominis
10.3969/j.issn.1671-8348.2024.08.004
- VernacularTitle:人型支原体致外科手术后切口感染的临床特征及耐药性分析
- Author:
Peng TANG
1
;
Di MOU
;
Yunying WANG
Author Information
1. 重庆医科大学附属第二医院检验科,重庆 400010
- Keywords:
Mycoplasma hominis;
surgical operation;
infection;
clinical characteristic;
drug sensitivity
- From:
Chongqing Medicine
2024;53(8):1137-1142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics and drug resistance of postoperative incision infection caused by Mycoplasma hominis (Mh).Methods A total of 8 cases of postoperative MH infection in this hospital from January 2020 to September 2022 were collected,and 8 subjects undergoing the physical ex-amination during the same period were selected as the healthy control group.The data of the disease cases conducted the summarized analysis.Results The Mh caused surgical infection sites were mainly concentrated in the surgical local incision,and the symptoms were manifested as mild redness,swelling,heat,pain and inci-sion poor healing.Moreover,the empirical treatment with β-lactam drugs showed the poor efficacy,and the in-fection cycle lasted for 11-24 d.After obtaining the microbiological evidence,the medication regimen was ad-justed to conduct the target treatment,the incision infection in the patients were effectively improved.Com-pared with the healthy control group,the white blood cell count,neutrophil granulocyte percentage and C reac-tive protein in the infection group were significantly elevated (P<0.01),while the procalcitonin level had no significant change (P>0.05).Mh was cultured in the blood agar medium for 48 h,only small needle-like colo-nies could be seen,moreover the bacteria with Gram stain was not stained.Mh showed good sensitivity to dox-ycycline,minocycline,josamycin,spectinomycin and gatifloxacin,but had high resistance rates to other macrol-ides,aminoglycosides and quinolones.Conclusion Mh caused surgical incision infection is relatively rare.Fully understanding the infection characteristics of this pathogen is beneficial to the diagnosis and treatment of the patients.
