Progress of diagnosis and treatment of myeloid sarcoma
10.3760/cma.j.cn115356-20230614-00134
- VernacularTitle:髓系肉瘤的诊疗进展
- Author:
Jingjing LIANG
1
;
Xialin ZHANG
;
Linhua YANG
Author Information
1. 山西医科大学第二医院血液科,太原 030001
- Keywords:
Myeloid sarcoma;
Diagnosis;
Imaging technology;
Chemotherapy;
Hematopoietic stem cell transplantation
- From:
Journal of Leukemia & Lymphoma
2024;33(8):509-512
- CountryChina
- Language:Chinese
-
Abstract:
Myeloid sarcoma (MS) is a solid tumor formed by extramedullary infiltration of primitive or immature cells of the myeloid lineage. Pathology is the gold standard for diagnosis, but the misdiagnosis rate is high. Immunohistochemical staining can reduce misdiagnosis. Molecular biology and cytogenetics are important complementary diagnostic indicators. Imaging techniques, especially fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT), are important for the diagnosis of MS. Acute myeloid leukemia (AML) chemotherapy regimen combined with hematopoietic stem cell transplantation is currently the main treatment for MS.