A Case of Systemic Lupus Erythematosus Associated With Myelofibrosis.
- Author:
Yang Sig KIM
1
;
Ho Gue KIM
;
Seng Dae CHOI
;
Yeung Jun WON
;
Young Bae SEO
;
Jae Hyuk JUNG
;
Hou Gun BAE
Author Information
1. Department of Internal Medicine, Han Dong University, Sulin Prebyterian Hospital, Pohang, Korea.
- Publication Type:Case Report
- Keywords:
Systemic lubpus erythematosus Myelofibrosis
- MeSH:
Adult;
Bone Marrow;
Collagen;
Female;
Fibronectins;
Humans;
Laminin;
Lupus Erythematosus, Systemic*;
Menorrhagia;
Myeloproliferative Disorders;
Primary Myelofibrosis*;
Syncope
- From:Korean Journal of Medicine
1998;55(1):127-130
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Myelofibrosis is characterized by excessive deposition of collagen, laminin and fibronectin within the bone marrow stroma. These change can be due to primary myeloproliferative disorders, a variety of malignant process, endocrine disturbances, or inflammatory disease. Clinical and laboratory finding are suggest in the immune process with myelofibrosis. It has been rarely reported that myelofibrosis coexisting with SLE. This is a case report of systemic lupus erythematosus coexisting with bone marrow fibrosis in a 44 years old female patient presenting with menorrhagia, syncope and palpitation. We report the case with relevant literature review. Treatment with corticosteroid in a patient with SLE and myelofibrosis remit to the clinical and hematologic abnormalities.
