Therapeutic Modulation of Gut Microbiota in Functional Bowel Disorders.

Author: Hyo Jeong LEE ¹ ; Jong Kyoung CHOI ; Han Seung RYU ; Chang Hwan CHOI ; Eun Hee KANG ; Kyung Sik PARK ; Yang Won MIN ; Kyoung Sup HONG
Author Information

1. Health Screening and Promotion Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Publication Type:Review
Keywords: Diet; Fecal microbiota transplantation; Irritable bowel syndrome; Microbiota; Probiotics
MeSH: Constipation; Diarrhea; Diet; Fecal Microbiota Transplantation; Gastrointestinal Diseases; Gastrointestinal Microbiome*; Irritable Bowel Syndrome; Lower Gastrointestinal Tract; Microbiota; Probiotics
From:Journal of Neurogastroenterology and Motility 2017;23(1):9-19
CountryRepublic of Korea
Language:English
Abstract: Functional bowel disorders (FBDs) are functional gastrointestinal disorders with symptoms attributable to the middle or lower gastrointestinal tract. These include irritable bowel syndrome, functional bloating, functional constipation, functional diarrhea, and unspecified FBD. Increasing evidence has emerged of late that intestinal microbiota is involved in the pathogenesis of FBDs. In this review, the therapeutic benefits and future perspectives of the currently available strategies for modifying the gut microbiota in FBDs are described, focusing primarily on irritable bowel syndrome and functional constipation.