Nursing of intracranial arterial recanalization in patients with acute infarction by urokinase intravasal thrombolysis double interventional therapy
10.3760/cma.j.issn.1674-2907.2010.31.011
- VernacularTitle:尿激酶双重溶栓联合机械性碎栓治疗急性脑梗死患者的护理
- Author:
Ming-Chun GAO
1
;
Shu-Qin CAO
;
Xian-Jun MENG
;
Xiu-Li WANG
;
Yue SHI
Author Information
1. 221004,徐州,解放军第九十七医院神经内科
- Keywords:
Cerebral infarction;
Urokinase;
Thrombolysis therapy;
Nursing
- From:
Chinese Journal of Modern Nursing
2010;16(31):3754-3756
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility and safety of urokinase intravasal thrombolysis double interventional therapy in patients with acute infarction. Methods 9 patients with acute cerebral infarction within 6h were in study group, 900 000 units of urokinase dissolved into 100 ml saline was used as intravenous drip for these patients, meanwhile, 3D DSA examination conducted to confirm cerebral artery of infarction and the position of thrombus, then mechanical thrombolysis by micro-guiding-wire and thrombolysis by small dose urokinase were done. 1 200 000 units of urokinase dissolved in 120 ml saline was used as intravenous drip in control group (16cases). Results 6 cases were generally cured, 1 case got marked effect, 2 cases were effective, 0 cases was inefficient, the rate of marked effect was 77. 8%, total effective rate was 100%;Corresponding results in control group were 2,1,5,8, rate of marked effect was 18.75%, total effective rate was 50%; the differences of marked effect rate and total effective rate in two groups were statistically significant( P ＜0.05). ESS score was (77.50 ±0.71) in study group and (62.25 ±5.95) in control group, the differences between two groups were statistically significant ( P ＜ 0. 05 ). Conclusions Urokinase intravasal thrombolysis double interventional therapy is safety and effective and can recanalize occlusive artery as soon an possible for acute cerebral infarction patients within 6 hours, it's a kind of feasible therapy. Nurse should establish green channel, strive time for thrombolysis, observe patient' condition closely and give appropriate nurse, then better curative effect can be achieved.
