Application and nursing about urokinase for the treatment of thrombosis in arteriovenous fistula in hemodialysis patients
10.3760/cma.j.issn.1674-2907.2010.22.006
- VernacularTitle:尿激酶在动静脉内瘘血栓形成患者中应用的护理
- Author:
Chun-Yuan TANG
1
;
Bi-Ning LIANG
;
Rao-Ping WANG
;
Wan-Na FENG
;
Ruo-Dan WANG
;
Lu-Ying WANG
Author Information
1. 510080广州,中山大学附属一院肾内科血液净化中心
- Keywords:
Hemodialysis;
Arteriovenous fistulae;
Thrombolysis;
Thrombus;
Nursing
- From:
Chinese Journal of Modern Nursing
2010;16(22):2620-2622
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of urokinase in the treatment of thrombosis in hemodialysis patients with arteriovenous fistulae and to discuss simple, safe and effective methods of thrombolysis. Methods Local injections of urokinase were applied in 23 hemodialysis patients for 43 times to treat thrombosis in fistula, then the effects were observed, and the changes between before treatment and after treatment of several index, such as activated partial thromboplastin time( APTT), Fibrinogen( Fbg), international normalized ratio (INR), Prothrombin Time (PT), thrombin time(TT) were compared. Results The thrombolytic therapies were used in 23 cases for 43 times in total, in which 33 times (76.7% ) received success, and there were no severe complications occurred. The effectiveness was related to the duration of thrombosis. There were no significant differences in comparison of APTT, Fbg, INR, PT, TT before and after urokinase administration. Conclusions Urokinase was effective in thrombolytic therapy for hemodialysis patients with thrombosis in arteriovenous fistula.
