Association between carotid intima-media thickness and Ankle-Brachial Index in patients with ischemic stroke.
- Author:
Young Mi YOON
1
;
Hyung Suk LEE
;
Shin Hye BAEK
;
Hye Lim LEE
;
Minju YEO
;
Seo Young CHOI
;
Ji Seon KIM
;
Sung Hyun LEE
;
Sang Soo LEE
;
Dong Ick SHIN
Author Information
1. Department of Neurology, Chungbuk National University Hospital, Chungbuk National University, College of Medicine, Cheongju 361-711, Korea. sdi007@hanmail.net
- Publication Type:Original Article
- Keywords:
ischemic stroke;
carotid;
intima media thickness;
ankle brachial index;
atherosclerosis
- MeSH:
Ankle Brachial Index*;
Arm;
Atherosclerosis;
Blood Pressure;
Carotid Arteries;
Carotid Intima-Media Thickness*;
Humans;
Leg;
Pulse Wave Analysis;
Retrospective Studies;
Stroke*;
Ultrasonography
- From:Journal of Biomedical Research
2014;15(2):68-71
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND PURPOSE: The Ankle-Brachial Index (ABI) is the ratio of blood pressure in the lower legs to that in the arms. The intima-media thickness (IMT) of extracranial carotid arteries determined by B-mode ultrasound is a measurable index of the presence of atherosclerosis. A low ABI and a high carotid IMT are independently related to increased risk of cardiovascular events. This study examined the association between carotid IMT and ABI in patients with ischemic stroke. MATERIALS AND METHODS: Retrospectively, 116 hospitalized patients with ischemic stroke were recruited. Using a pulse wave velocity ABI device along with carotid duplex sonography, we measured carotid IMT and ABI and investigated the correlation between average values. RESULTS: There was a significant difference in carotid IMT between the normal and abnormal ABI groups (P=0.0262). The group with an abnormal ABI was more than five times as likely to have increased carotid IMT as the group with a normal ABI (age, sex-adjusted OR 5.67 (95% CI 1.85~17.38)). The ABI and carotid IMT showed a weak inverse linear correlation in patients with ischemic stroke (correlation coefficient -0.378 after adjusting for age and sex). CONCLUSION: Our study suggests that an abnormal ABI is associated with a high carotid IMT in patients with ischemic stroke.
