Experimental Study of Rehabilitation of Rats with Anal Edema with Traditional Chinese Medicine
10.3760/cma.j.issn.1674-2907.2009.36.007
- VernacularTitle:大鼠肛门水肿中药坐浴治疗的实验研究
- Author:
Xiu-Jun GUO
1
;
Juan QIN
;
Xiao-Yin ZHAO
;
Yu-Hua BIAN
;
Yuan DU
;
Xiang JIN
Author Information
1. 南京中医药大学第三附属医院
- Keywords:
Aanal Edema;
Hip Bathing;
Traditional Chinese Medicine (TCM);
Animal Experiment
- From:
Chinese Journal of Modern Nursing
2009;15(36):3860-3864
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of different time duration hip bathing with traditional Chinese medicine for rehabilitation of rats with anal edema, which can provide evidence for a best effective hip bathing method in the clinical application. Methods The rat model of anal edema was induced with carrageenan injection. Ninty six SD rats were divided into early intervene and latter intervene batches, every batches were randomly divided into six groups; normal control group 1, normal control group2, model matched groupl, model matched group2, hip bathing with TCM groupl, hip bathing with TCM group2. Hip bathing time duration were lOminutes and 20minutes. The rehabilitation of rats anal edema were observed. Results The comparison has been made among edema area, the ratio of dry/wet weight, microcirculation change, skin temperature, the difference is statistically significant in TCM early intervene hip bathing groups (P < 0. 05). There was a significant difference of edema proportion with 20 minutes duration between TCM hip bathing groups and model control groups (P < 0. 01 ). The comparison has been made among the ratio of dry/wet weight, microcirculation change, the difference is statistically significant in TCM latter intervene hip bathing groups(P< 0. 05). Histopathological examination showed local tissue inflammatory cell infiltration, the loosen degree of tissue space and capillary congestion of modle group were improved. Conclusions Hip bathing with traditional Chinese medicine in early intervene have obvious effect on rehabilitation of rats with anal edema, which can dispell anal edema, improving microcirculation could descend the temperature and promote the rehabilitation of anal edema, relieve inflammation and hyperemia. In the respect of edema proportion relieving, hip bathing with 20 minutes duration showed better effect than 10 minutes.
